How Does NutriNerve® Work?

 The formula works to help your body repair itself on a cellular level, and contains ingredients designed to decrease inflammation, rebuild and restore nerve health, and reduce the underlining cause of peripheral diabetic neuropathy — oxidative stress. Neuropathic pain is a result of diseased nerves and is not the result of trauma or injury, and it cannot be treated in the same way as normal pain. Dr. Vinik has determined that much of the pain that patients suffering from neuropathic pain and peripheral nerve damage experience is the result of oxidative stress. The nutrients in NutriNerve® work at the cellular level to reduce this oxidative stress and decrease the pain and inflammation that it produces. NutriNerve ingredients help the body to rebuild and restore nerve health naturally, allowing it to restore nerve signal transmission and improve microvascularity.

NutriNerve Ingredients

NutriNerve® Ingredients

Gamma Linolenic Acid (GLA) has been shown to restore nerve conduction velocity in animals that have had a 25% decrease in nerve conduction velocity due to diabetes [iii]. Additionally it has been used to treat rheumatoid arthritis, acute respiratory distress syndrome, stress, and premenstrual syndrome. GLA is derived from borage seed oil, which has been used to reduce pain and swelling, prevent heart disease, and even to protect against stroke.
Alpha Lipoic Acid (ALA) has been shown in placebo controlled randomized studies to improve diabetic neuropathy symptoms. In the SYDNEY 2 trial, there was demonstrated to be a 52% decrease in the amount of pain experienced (including stabbing pain, burning pain, paresthesia, and asleep numbness of the feet) after five weeks of 600 mg ALA [i]. The results of this four year study show clinically meaningful improvement and delay in the progression of diabetic neuropathy. ALA is also attributed with improving blood flow via vasodilation of the brachial artery [ii].
Benfotiamine (Vitamin B-1) – A statistically significant (p = 0.0287) improvement in the neuropathy score was observed in a group given benfotiamine [iv]. It is often prescribed in Germany as a treatment for sciatica and other neuropathic pain complaints.
Vitamin D enhances the absorption of important minerals and specifically addresses the vitamin deficiency common to type 1 and 2 diabetes. It has been shown to reduce the severity of diabetic neuropathy. [vi]
Vitamin B-12 is important to the normal functioning of the nervous system, DNA synthesis and overall metabolism, and has been shown to relieve the symptoms of paraesthesia. Vitamin B-12 restores blood flow which produces myelin synthesis, a fatty substance that protects the nerve fibers. [vii]
NUTRINERVE® PRODUCT INFORMATION
Disclaimer: Results may vary. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Notes:
[i] Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diabetes Care. 2006 Nov;29(11):2365-70
[ii] Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) study. Circulation. 2005 Jan 25;111(3):343-8. Epub 2005 Jan 17.
[iii] Beneficial effects of gamma linolenic acid supplementation on nerve conduction velocity, Na+, K+ ATPase activity, and membrane fatty acid composition in sciatic nerve of diabetic rats.J Nutr Biochem. 1999 Jul;10(7):411-20.
[iv] Benfotiamine in the treatment of diabetic polyneuropathy–a three-week randomized, controlled pilot study (BEDIP study). Int J Clin Pharmacol Ther. 2005 Feb;43(2):71-7.[v] Lipid independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients Am Heart Journal 2005; 149, 471
[vi] Reversal of the Symptoms of Diabetic Neuropathy through Correction of Vitamin D Deficiency in a Type 1 Diabetic Patient, Published online
[vii] Effectiveness of vitamin B12 on diabetic neuropathy: systematic review of clinical controlled trials. Acta Neurol Taiwan. 2005 Jun;14(2):48-54.
For additional articles see our References Page.